Recovery Calculations : Better Data Driving Better Decisions

Recovery Calculations

Researchers used to Microdialysis will want to know more about recovery calcualations. With OFM, it's a little different. Learn more in this section.

Is there a recovery factor for cOFM probes? What are the factors that influence recovery of molecules through cOFM probes in vivo? Is dilution of ISF a factor?

cOFM can be calibrated (=recovery estimation) for absolute quantification of substances in the brain. Influencing factors are the size of open length, flow ...

Fri, 3 Aug, 2018 at 11:36 AM

What is the principle of in vitro recovery in cOFM. How does it differ to microdialysis? What is the relevance of in vitro recovery with cOFM?

The in vitro recovery of cOFM assesses the adsorption of the substance of interest to the cOFM system. In vitro recovery tests should be done with the same ...

Fri, 3 Aug, 2018 at 11:42 AM

What is the best way to calculate in vivo recovery using cOFM probes?

In vivo recovery is assessed empirically. Commonly used protocols can be found in the literature (e.g. no net flux method, retrodialysis etc.). The in vivo c...

Fri, 3 Aug, 2018 at 11:44 AM