The in vitro recovery of cOFM assesses the adsorption of the substance of interest to the cOFM system. In vitro recovery tests should be done with the same system components that are used in the in vivo setup (cOFM probe type, tubing sets, etc.). Once the adsorption is assessed, in vitro recovery can be used as a correction factor for in vivo results. In vitro recovery cannot be used as an in vivo recovery surrogate.
What is the principle of in vitro recovery in cOFM. How does it differ to microdialysis? What is the relevance of in vitro recovery with cOFM? Print
Modified on: Fri, 3 Aug, 2018 at 11:42 AM
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